An Upstream Finite Volume Scheme for a Bone Healing Model

Authors

  • Alexandre Uzureau UniversitГ© de Nantes
  • Yves Coudiere
  • Mazen Saad

DOI:

https://doi.org/10.11145/j.biomath.2012.09.254

Keywords:

bone growth, finite volume method, numerical simulation

Abstract

This paper is devoted to the introduction of a numerical scheme for a bone healing model and simulation of skull fractures. The mathematical model describes the evolution of mesenchymal stem cells, osteoblasts, bone matrix and osteogenic growth factor. WeВ propose a numerical scheme based on an implicit finite volume method constructed on an orthogonal mesh. The efficiency and robustness of the scheme are shown in simulating a skull fracture in rats.

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Published

2012-09-28

Issue

Section

Original Articles